The small percentage that do make it to launch, however, more than make up for the cash spent on those that don’t. That is the nature of drug development with one group estimating only 6% to 7% of new chemical entities that commence clinical trials reach launch (Dowden & Munro (2019) Nat Rev Drug Discov). Given the high nature of the hurdle, in our original initiating coverage report on KZA, we only gave paxalisib a small chance of returning a positive result from the overall study. Demonstrating efficacy in GBM is an extremely high hurdle as shown by the fact that there is only one approved drug for the disease, temozolomide, and it is only effective in 1/3 of patients. The study was an adaptive trial designed to assess the potential of new therapeutics to treat the highly aggressive brain cancer glioblastoma (GBM) in a cost-effective manner. Kazia Therapeutics (KZA) announced yesterday morning that paxalisib did not meet the threshold to move into stage 2 of the GBM AGILE clinical trial (NCT03970447). Cash on hand of $3.6m (2QįY23) is likely sufficient to fund operations until breakeven is reached.ĭOWNLOAD RESEARCH REPORT Paxalisib Misses AGILE Hurdle, but Very Significant Value Remains Investors Over-React, Smart Ones Will Profit Represents sufficient scale to reach profitability. The company has built a significant new contract pipeline in recent quartersĪnd is targeting c.15,000 subscribers on its platform by Dec 2023, which There is a growing recurring revenueĬomponent built on SaaS-based subscriptions to its platform. The market is very fragmented, with no competitor offering CTQ’sĬTQ’s income stream is non-discretionary and largely funded by federal and Technology innovation and recommendations from the Royal Commission intoĪged Care. Products, driven by the ageing population, rising costs and labour shortages, The health-tech industry enjoys significant tailwinds for assistive living Include falls detection, vital signs monitoring and medication management. Home care, disability care and personal security sectors. (Sofihub) with a portfolio of best-in-class solutions for the global aged care, That brought the total dividend payout for the 2020 financial year to 28 cents a share, down from 38 cents a share the year before.ĬTQ has developed a leading proprietary assistive living technology platform The company will pay a final dividend of 8 cents a share, down from 20 cents a share for the final half of 2018-19. Treasury Wine Estates said the ongoing uncertainty induced by the pandemic had made it unable to provide earnings outlooks for the 2021 financial year – it’s not alone in that respect. That’s the highest the shares have been since late January when a poor trading update triggered doubts about the company’s ability to match 2018-19’s performance and sent the shares plunging. The suggestions of an upturn in Asian and especially sales into China sparked a 12% plus surge in the TWE share price yesterday and it ended at $12.85. TWE said volumes sold in the Chinese market had risen 40% in June compared to the previous corresponding month. However, the company said on Thursday that it had noticed an upturn in Asian consumption and sales in the final quarter of the financial year 2020. It also noted the challenging wine market conditions in the US had also impacted sales within its key wine channels, with overall North American earnings before tax and interest slumping 37% to $147.3 million.Įarnings before interest and tax from Asian exports fell 14% to $243.7 million, while Australian and New Zealand EBIT declined 16% to $133.3 million. TWE said its E-commerce sales across its global distributions had accelerated in the second half of the year, as a result of lockdown measures imposed across the world. Like so many other companies the online performance improved because of the lockdowns. The company said the second half of the 2020 financial year was riddled with unfavourable volumes and portfolio mixes as a result of COVID-19, which had reduced the demand for luxury wine sales, especially in markets like Australia, China, and the US. The surge in the share price yesterday in the wake of the 2019-20 annual results suggest it might now be returning to the market’s good books, especially with hints of an upturn in demand in China.Īfter a volatile six months of pandemic, bushfires, weak marketing, stock problems and a change in senior management Treasury Wine Estates has reported a 25% slide in net profit to $315.8 million for the 12 months ending June 30. Have investors forgiven Treasury Wine Estates (TWE) after the poor updates and other headwinds in the first six months of 2020?
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |